Journal of Clinical & Experimental Nephrology

Study to assess the Characteristics of Blood Pressure in Chronic Kidney Disease

Background: Hypertension is an important modifiable risk factor for many complications. Hence, regulation of BP may substantially reduce the risk of cardiovascular events and slow the decline in kidney function. Hypertension is a major risk factor in the progression of Chronic Kidney Disease (CKD). Hypertension occurs in 86% of patients with CKD however, the proportion of patients who are able to maintain Blood Pressure (BP) control of <130⁄80 mmHg remains poor.

Objective: To assess the characteristics of blood pressure in chronic kidney disease.

Materials and Methods: A cross sectional study was conducted at a tertiary care centre in South India from 1st of January 2016 to 31^st of July 2017. A total of 124 cases were included in the study.

Results: In our study 10.5% were in the age group <30 years. We reported that 33.1% had stage 3 CKD, 35.5% had stage 4 CKD and 31.5% had stage 5 CKD. There was significant difference in mean office SBP and mean office DBP with increase in stage of CKD. Mean OSBP and ODBP was increasing with increase in stage of CKD.

Conclusion: Evaluation of ambulatory BP also showed a remarkable amount of overestimation (white coat HTN) and underestimation (masked HTN) of BP among patients with CKD. Hence, using ABPM can circumvent errors in measurement of BP and also helpful in proper management of HTN in CKD.

Author(s): Mohammed Fahad Khan

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