Acute kidney injury (AKI) is a severe case of kidney failure that is caused by the build-up of waste products in your blood making it impossible for your kidneys to maintain adequate fluid balance in your body. AKI is caused by reduced blood flow to the kidneys as it is evident that kidneys have the highest blood flow because they are the body's natural filtration system. This reduced blood flow could be caused by low blood volume after bleeding, excessive vomiting or diarrhoea, or severe dehydration ultimately blood coagulation disorders. Coagulopathy is a disorder in which the capacity of blood to clot is diminished. It may cause impulsive internal or external bleeding when left untreated.
Milagros D. Samaniego-Picota